On August 19, 1297, a young man of royal heritage died in the household of the Count of Provence and King of Naples at Brignoles, a short distance from Marseille. The young man was Louis of Anjou, a Franciscan friar and Bishop of Toulouse, who had renounced his inheritance and claim to the Kingdom of Naples to pursue a religious vocation. Only twenty-three years old when he died, Louis nevertheless had long been inspired by Franciscan spirituality, and less than eight (...) months before had realized his dream of professing vows within the Order of Friars Minor at the same time that he submitted to consecration as Bishop of Toulouse. In March of the following year, Peter of John Olivi, a native son of .. (shrink)

When women won the vote in the United States in 1920 they were still routinely barred from serving as jurors, but some began vigorous campaigns for a place in the jury box. This book tells the story of how women mobilized in fifteen states to change jury laws so that women could gain this additional right of citizenship. Some campaigns quickly succeeded; others took substantially longer. The book reveals that when women strategically adapted their tactics to the broader political environment, (...) they were able to speed up the pace of jury reform, while less strategic movements took longer. A comparison of the more strategic women's jury movements with those that were less strategic shows that the former built coalitions with other women's groups, took advantage of political opportunities, had past experience in seeking legal reforms and confronted tensions and even conflict within their ranks in ways that bolstered their action. (shrink)

When Congress passed the 19th Amendment in 1919 granting women voting rights, 13 western states had already adopted woman suffrage. Only 2 states outside the West had done so. Using event history analysis, the authors investigate why woman suffrage came early to the western states. Alan Grimes's hypotheses, that native-born, western men were willing to give women the vote to remedy western social problems and to increase the number of women in the region, receive little support in our analysis. Rather, (...) this study finds that woman suffrage came to the West because of the mobilization of the western suffrage movements and because of political and gendered opportunities existing in that region. (shrink)

Many individuals have experienced a multitude of chronic stressors and diminished psychological functioning during COVID-19. The current study examined whether biases towards positive social media or positive autobiographical memories was related to increases in psychological functioning during COVID-19. Participants were 1071 adults (Mage = 46.31; 58% female; 78% White) recruited from MTurk. Participants reported on their social media consumption and autobiographical recall, positive and negative affect, and dysphoria symptoms. Results indicated that, at the first assessment collected in the spring and (...) summer of 2020, positively biased social media consumption was cross-sectionally related to higher levels of positive affect, and positively biased autobiographical recall was cross-sectionally related to lower levels of negative affect and dysphoria symptoms. Sensitivity analyses examined cross-sectional relations from a second assessment collected in fall 2020, and prospective cross-lagged analyses. The findings point to potential psychological benefits of positive biases during chronic stressors. (shrink)

Within the cognitive sciences, most researchers assume that it is the job of linguists to investigate how language is represented, and that they do so largely by building theories based on explicit judgments about patterns of acceptability – whereas it is the task of psychologists to determine how language is processed, and that in doing so, they do not typically question the linguists' representational assumptions. We challenge this division of labor by arguing that structural priming provides an implicit method of (...) investigating linguistic representations that should end the current reliance on acceptability judgments. Moreover, structural priming has now reached sufficient methodological maturity to provide substantial evidence about such representations. We argue that evidence from speakers' tendency to repeat their own and others' structural choices supports a linguistic architecture involving a single shallow level of syntax connected to a semantic level containing information about quantification, thematic relations, and information structure, as well as to a phonological level. Many of the linguistic distinctions often used to support complex syntactic structure are instead captured by semantics; however, the syntactic level includes some specification of “missing” elements that are not realized at the phonological level. We also show that structural priming provides evidence about the consistency of representations across languages and about language development. In sum, we propose that structural priming provides a new basis for understanding the nature of language. (shrink)

Economics is probably the most subtle, precise and powerful of the social sciences and its theories have deep philosophical import. Yet the dominant alliance between economics and philosophy has long been cheerfully simple. This is the textbook alliance of neo-Classicism and Positivism, so crucial to the defence of orthodox economics against by now familiar objections. This is an unusual book and a deliberately controversial one. The authors cast doubt on assumptions which neo-Classicists often find too obvious to defend or, indeed, (...) to mention. They set out to disturb an influential concensus and to champion an unpopular cause. Although they go deeper into both philosophy and economics than is usual in interdisciplinary works, they start from first principles and the text is provokingly clear. This will be a stimulating book for all economic theorists and philosophers interested in the philosophy of science and social science. (shrink)

Geoengineering has been broadly and helpfully defined as “the intentional manipulation of the earth's climate to counteract anthropogenic climate change or its warming effects” (Corner and Pidgeon , 26). Although there exists a rapidly growing literature on the ethics of geoengineering, very little has been written about its gender dimensions. The authors consider four contexts in which geoengineering appears to have important gender dimensions: (1) the demographics of those pushing the current agenda, (2) the overall vision of control it involves, (...) (3) the design of the particular technologies, and (4) whom geoengineering will most affect and benefit. After detailing these four gender dimensions, we consider three ways in which the geoengineering discourse could be enriched if it became more sensitive to issues of gender. These include increasing the focus on the concrete other, recognizing the socially transformative potential of geoengineering technologies, and engaging in value-sensitive design. Although ultimately remaining agnostic on the desirability of geoengineering, the paper brings gender considerations into a discussion from which they have been conspicuously absent. (shrink)

Structural priming offers a powerful method for experimentally investigating the mental representation of linguistic structure. We clarify the nature of our proposal, justify the versatility of priming, consider alternative approaches, and discuss how our specific account can be extended to new questions as part of an interdisciplinary programme integrating linguistics and psychology as part of the cognitive sciences of language.

Levelt, Roelofs, & Meyer (henceforth Levelt et al. 1999) propose a model of production incorporating a lemma stratum, which is concerned with the syntactic characteristics of lexical entries. We suggest that syntactic priming experiments provide evidence about how such syntactic information is represented, and that this evidence can be used to extend Levelt et al.'s model. Evidence from syntactic priming experiments also supports Levelt et al.'s conjecture that the lemma stratum is shared between the production and comprehension systems.

Volume 19, Issue 9, September 2019, Page 1-4.

This collection of essays, drawn from the latest generation of Whitehead scholars, explores how, in the deconstruction of certain concepts, an unceasing invitation of possibility and change is released, both in relation to ongoing philosophical conversations, and as applied to lived experience. The essays make a significant intervention in the field of Whiteheadian scholarship by creating new intersections and paths that extend Whitehead's thought in novel, and often unexpected, directions. The philosophy of Alfred North Whitehead proposes a radical reconceptualization of (...) experience-one in which we, and all other things, are composed of mutually implicated series of events in an infinite universe of interaction, generating and regenerating experience. Far from indicating a new superlative of holistic integrity, Whitehead prefers the always incomplete movement of all realities, which is the source of vitality for every new generation. This volume applies Whitehead's philosophy to superlatives-those valued concepts that limit and define our categories amid the flux of experience. The first half of this book probes the superlatives that have historically defined philosophical method in the West. These essays trace the adventures of concepts like substance, novelty, system, and truth. Ossified oppositions that define these superlatives are fractured, indicating new directions for growth. The essays in the second half of the book reflect on the influx, fragility, and impossibility of superlatives like care, tragedy, love, and loss in human experience, generating new matters of philosophical discourse. Superlatives abound. But Whitehead cautions us to attend to their multiplicity. The mutual immanence of events constantly generates new constellations of importance, and so superlatives, because they are contingent upon unstable modes of togetherness, cannot be taken for granted. Any of these concepts may have a particular significance today, but as events coalesce into new constellations, those ideals will continue to take on new meaning. (shrink)

Previous studies have documented the fallibility of attempts by surrogates and physicians to act in a substituted judgment capacity and predict end-of-life treatment decisions on behalf of patients. We previously reported that physicians misperceive their patients' preferences and substitute their own preferences for those of their patients with respect to four treatments: cardiopulmonary resuscitation (CPR) in the event of cardiac arrest, ventilator for an indefinite period of time, medical nutrition and hydration for an indefinite period of time, and hospitalization in (...) the event of pneumonia. (shrink)

The History and Philosophy of Science: A Reader brings together seminal texts from antiquity to the end of the nineteenth century and makes them accessible in one volume for the first time. With readings from Aristotle, Aquinas, Copernicus, Galileo, Descartes, Newton, Lavoisier, Linnaeus, Darwin, Faraday, and Maxwell, it analyses and discusses major classical, medieval and modern texts and figures from the natural sciences. Grouped by topic to clarify the development of methods and disciplines and the unification of theories, each section (...) includes an introduction, suggestions for further reading and end-of-section discussion questions, allowing students to develop the skills needed to: § read, interpret, and critically engage with central problems and ideas from the history and philosophy of science § understand and evaluate scientific material found in a wide variety of professional and popular settings § appreciate the social and cultural context in which scientific ideas emerge § identify the roles that mathematics plays in scientific inquiry Featuring primary sources in all the core scientific fields - astronomy, physics, chemistry, and the life sciences - The History and Philosophy of Science: A Reader is ideal for students looking to better understand the origins of natural science and the questions asked throughout its history. By taking a thematic approach to introduce influential assumptions, methods and answers, this reader illustrates the implications of an impressive range of values and ideas across the history and philosophy of Western science. (shrink)

Newborn bloodspot screening programs are some of the longest running population screening programs internationally. Debate continues regarding the need for parents to give consent to having their child screened. Little attention has been paid to how meanings of consent-related terminology vary among stakeholders and the implications of this for practice. We undertook semi-structured interviews with parents, healthcare professionals and policy decision makers in two Canadian provinces. Conceptions of consent-related terms revolved around seven factors within two broad domains, decision-making and information (...) attainment. Decision-making comprised: parent decision authority; voluntariness; parent engagement with decision-making; and the process of enacting choice. Information ascertainment comprised: professional responsibilities ; parent responsibilities; and the need for discussion and understanding prior to a decision. Our findings indicate that consent-related terms are variously understood, with substantive implications for practice. We suggest that consent procedures should be explained descriptively, regardless of approach, so there are clear indications of what is expected of parents and healthcare professionals. Support systems are required both to meet the educational needs of parents and families and to support healthcare professionals in delivering information in a manner in keeping with parent needs. (shrink)

We argue that the universal recommendations against “off-label” pediatric use of approved COVID-19 issued by the FDA, CDC, and AAP are overbroad. Especially for higher-risk children, vaccination can be ethically justified even before FDA authorization or approval – and similar reasoning is relevant for even younger patients. Legal risks can also be managed, although the FDA, CDC, and Department of Health and Human Services (HHS) should move quickly to provide clarity.

Mister Rogers’ Neighborhood, which began as The Children’s Corner in 1953 and terminated in 2001, left its mark on America. The show’s message of kindness, simplicity, and individual uniqueness made Rogers a beloved personality, while also provoking some criticism because, by arguing that everyone was special without having to do anything to earn it, the show supposedly created an entitled generation. -/- In Mister Rogers and Philosophy, thirty philosophers give their very different takes on the Neighborhood phenomenon.

Parental reading to young children is well-established as being positively associated with child cognitive development, particularly their language development. Research indicates that a particular, “intersubjective,” form of using books with children, “Dialogic Book-sharing”, is especially beneficial to infants and pre-school aged children, particularly when using picture books. The work on DBS to date has paid little attention to the theoretical and empirical underpinnings of the approach. Here, we address the question of what processes taking place during DBS confer benefits to (...) child development, and why these processes are beneficial. In a novel integration of evidence, ranging from non-human primate communication through iconic gestures and pointing, archaeological data on Pre-hominid and early human art, to experimental and naturalistic studies of infant attention, cognitive processing, and language, we argue that DBS entails core characteristics that make it a privileged intersubjective space for the promotion of child cognitive and language development. This analysis, together with the findings of DBS intervention studies, provides a powerful intellectual basis for the wide-scale promotion of DBS, especially in disadvantaged populations. (shrink)

Previous studies have documented the fallibility of attempts by surrogates and physicians to act in a substituted judgment capacity and predict end-of-life treatment decisions on behalf of patients. We previously reported that physicians misperceive their patients' preferences and substitute their own preferences for those of their patients with respect to four treatments: cardiopulmonary resuscitation in the event of cardiac arrest, ventilator for an indefinite period of time, medical nutrition and hydration for an indefinite period of time, and hospitalization in the (...) event of pneumonia. (shrink)

In her recent paper ‘The Epistemology of Propaganda’ Rachel McKinnon discusses what she refers to as ‘TERF propaganda’. We take issue with three points in her paper. The first is her rejection of the claim that ‘TERF’ is a misogynistic slur. The second is the examples she presents as commitments of so-called ‘TERFs’, in order to establish that radical (and gender critical) feminists rely on a flawed ideology. The third is her claim that standpoint epistemology can be used to establish (...) that such feminists are wrong to worry about a threat of male violence in relation to trans women. In Section 1 we argue that ‘TERF’ is not a merely descriptive term; that to the extent that McKinnon offers considerations in support of the claim that ‘TERF’ is not a slur, these considerations fail; and that ‘TERF’ is a slur according to several prominent accounts in the contemporary literature. In Section 2, we argue that McKinnon misrepresents the position of gender critical feminists, and in doing so fails to establish the claim that the ideology behind these positions is flawed. In Section 3 we argue that McKinnon’s criticism of Stanley fails, and one implication of this is that those she characterizes as ‘positively privileged’ cannot rely on the standpoint-relative knowledge of those she characterizes as ‘negatively privileged’. We also emphasize in this section McKinnon’s failure to understand and account for multiple axes of oppression, of which the cis/trans axis is only one. (shrink)

Rare genetic diseases collectively impact millions of individuals in the United States. These patients and their families share many challenges including delayed diagnosis, lack of knowledgeable providers, and limited economic incentives to develop new therapies for small patient groups. As such, rare disease patients and families often must rely on advocacy, including both self-advocacy to access clinical care and public advocacy to advance research. However, these demands raise serious concerns for equity, as both care and research for a given disease (...) can depend on the education, financial resources, and social capital available to the patients in a given community. In this article, we utilize three case examples to illustrate ethical challenges at the intersection of rare diseases, advocacy and justice, including how reliance on advocacy in rare disease may drive unintended consequences for equity. We conclude with a discussion of opportunities for diverse stakeholders to begin to address these challenges. (shrink)

We have synthesized a 582,970-base pair Mycoplasma genitalium genome. This synthetic genome, named M. genitalium JCVI-1.0, contains all the genes of wild-type M. genitalium G37 except MG408, which was disrupted by an antibiotic marker to block pathogenicity and to allow for selection. To identify the genome as synthetic, we inserted "watermarks" at intergenic sites known to tolerate transposon insertions. Overlapping "cassettes" of 5 to 7 kilobases (kb), assembled from chemically synthesized oligonucleotides, were joined by in vitro recombination to produce intermediate (...) assemblies of approximately 24 kb, 72 kb ("1/8 genome"), and 144 kb ("1/4 genome"), which were all cloned as bacterial artificial chromosomes in Escherichia coli. Most of these intermediate clones were sequenced, and clones of all four 1/4 genomes with the correct sequence were identified. The complete synthetic genome was assembled by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae, then isolated and sequenced. A clone with the correct sequence was identified. The methods described here will be generally useful for constructing large DNA molecules from chemically synthesized pieces and also from combinations of natural and synthetic DNA segments. 10.1126/science.1151721. (shrink)

The authors' claim that analogical reasoning is the product of relational priming is compatible with language processing work that emphasizes the role of low-level automatic processes in the alignment of situation models in dialogue. However, their model ignores recent behavioral evidence demonstrating a effect on relational priming. We discuss implications of these data.

Participants in clinical research sometimes view participation as therapy or exaggerate potential benefits, especially in phase I or phase II trials. We conducted this study to discover what methods might improve cancer patients’ understanding of early-phase clinical trials. We randomly assigned 130 cancer patients from three U.S. medical centers who were considering enrollment in a phase I or phase II cancer trial to receive either a multimedia intervention or a National Cancer Institute pamphlet explaining the trial and its purpose. Intervention (...) participants were 32 times more likely to believe that the trial’s purpose was to examine safety and 60 % less likely to believe they would experience long-term benefit or cure. There was no difference in enrollment decision. However, while patients’ understanding of the trial’s purpose improved and expectations of long-term benefit diminished, half the respondents still believed they would experience long-term benefit or cure from participation. Therefore, we conclude that multimedia interventions such as this one may help oncologists to explain the risks and benefits of early-phase cancer trials in a way that patients can more easily understand, helping them to make more informed decisions about participation. But further research into other factors that influence patients’ beliefs about the outcome of enrollment is needed, both to modify the interventions and to determine how malleable patient beliefs are. (shrink)

Researchers tracking social trends have discovered a remarkable labor-saving device called the computer. They sit down before the instrument, call up a search engine, enter a key word that they believe represents the trend, and count the number of articles aroused by that key word. They track these numbers over a period of time and even graph them. Those who dislike a certain concept are happy to report the concept's rise and fall. Such has occurred with two articles, one of (...) which appeared in CQ, reporting the rise and fall of medical futility. We are impressed with the power of this research methodology, which seems capable of eliminating concepts, even when our own more labor-intensive yet apparently less perceptive daily experience finds evidence of their existence all around us. (shrink)

That freedom involves a power to choose is a natural idea. But it requires a model of man which English philosophers have usually rejected. It requires an agent equipped with a will, who is faced with genuine alternatives and is, in some sense, autonomous. So it is rejected both by those, like Hobbes, who hold a strong version of determinism and by those, like Hume, who deny the existence of an autonomous self. The will, says Hobbes, is simply ‘the last (...) appetite in deliberating’. A mind, says Hume, is ‘nothing but a heap or collection of different perceptions, united together by certain relations’. The way is then apparently open for a denial that men ever act freely at all and so for a thoroughly deterministic basis for the social sciences. But this is not the usual conclusion. Hobbes and Hume both agree that there is no conflict between freedom and determinism, once ‘freeedom’ is properly understood. A man is free when he can get what he wants. As Hobbes puts it, ‘liberty is the absence of all impediments to action which are not contained in the nature and intrinsical quality of the agent’. In other words freedom does not involve choice but consists instead in the power to satisfy desire. (shrink)